Pre-exposure prophylaxis or PrEP is the use of an antiretroviral medication to prevent the acquisition of HIV infection by uninfected persons. PrEP is taken orally, using an antiretroviral drug available for treatment of HIV infection (tenofovir plus emtricitabine), The most common brand name of oral medication used for PrEP is Truvada. Although generic formulations are available in many countries at lower prices
The World Health Organization (WHO) now recommends that people at substantial risk of HIV should be offered PrEP as an additional prevention choice . In 2014 WHO recommended offering PrEP to men who have sex with men (MSM). On the basis of further evidence of the effectiveness and acceptability of PrEP, WHO has now broadened the recommendation to include all population groups at substantial risk of HIV infection.